Click Here to return To Results

 

Measurement of Acetylcholinesterase by PET in the Brains of Healthy Controls & Pts with Alzheimer's Disease Lancet 349:1805-1809, Iyo,M.,et al, 1997 See this aricle in Pubmed Article Abstract The estimated acetylcholinesterase distribution in the brain of the control participants agree with the acetylcholinesterase distribution at necropsy.All patients with Alzheimer's disease had multiple cortical regions with a reduced estimated acetylcholinesterase activity in comparison with control participants.The reduction was more pronounced in the parietotemporal cortex,with an average reduction rate of 31%in temporal and 38%in parietal cortex,and less pronounced in other cortical lesions(19%in frontal,24%in occipital,and 20%in sensorimotor cortex).Each patient was found to have at least two cortical regions with significantly reduced acetylcholinesterase activity.

Related Tags

(click to filter results - removes previous filter) acetylcholinesterase Alzheimer's disease CAT scan CAT scan,abnormal CAT scan,emission CAT scan,emission,abnormal

Click Here to return To Results